PCOS Polycystic Ovarian Syndrome (PCOS) is one of the most common female endocrine disorders and is a leading causes of female infertility. Herbal medicine, nutritional supplementation, dietary and lifestyle approaches can address the causes of PCOS and treat the symptoms of this condition naturally, without the use of pharmacological drugs.
PCOS Polycystic Ovarian Syndrome (PCOS) effects approximately 5%-10% of women of reproductive age (12–45 years old) and is thought to be one of the leading causes of female infertility. The principal features are obesity, anovulation (resulting oligomenorrhoea less than 8 periods a year)) or amenorrhoea (no menstruation), acne, and excessive amounts or effects of androgenic (masculinising) hormones. The symptoms and severity of the syndrome vary greatly among women. While the causes are unknown, insulin resistance, diabetes and obesity are all strongly correlated with PCOS.
PCOS can present in any age during the reproductive years. Due to its often vague presentation it can take years to reach a diagnosis. Serum insulin, insulin resistance and homocysteine levels are significantly higher in subjects having PCOS but have no significant effect on fertility.
Symptoms of PCOS may include some or all of the following:
- Oligomenorrhoea, amenorrhoea — irregular, few, or absent menstrual periods.
- Infertility, generally resulting from chronic anovulation (lack of ovulation).
- Hirsutism (increased abnormal, male pattern hair growth.
- Approximately three-fourths of patients with PCOS have evidence of hyperandrogenaemia (high androgen levels)
Excessive mild symptoms of hyperandrogenism such as acne or hypermenorrhoea are frequent in adolescent girls and are often associated with irregular menstrual cycles. In most instances, these symptoms are transient and only reflect the immaturity of the hypothalamic-pituitary-ovarian axis during the first years following menarche.
- Case history taking, specifically for menstrual pattern, obesity, hirsutism, and the absence of breast development.
- Gynaecologic ultrasonography is the major diagnostic tool, specifically looking for small ovarian follicles. These are believed to be the result of disturbed ovarian function with failed ovulation, reflected by the infrequent or absent menstruation that is typical of the condition. In normal menstrual cycle one egg is released from a dominant follicle - essentially a cyst that bursts to release the egg. After ovulation the follicle remnant is transformed into a progesterone producing corpus luteum, which shrinks and disappears after approximately 12–14 days. In PCOS, there is a so-called "follicular arrest", i.e., several follicles develop to a size of 5–7 mm, but not further. According to the Rotterdam criteria, 12 or more small follicles should be seen in a ovary on ultrasound examination. The follicles may be oriented in the periphery, giving the appearance of a 'string of pearls'. The numerous follicles contribute to the increased size of the ovaries, that is, 1.5 to 3 times larger than normal.
- Laparoscopic examination may reveal a thickened, smooth, pearl-white outer surface of the ovary. (This would usually be an incidental finding if laparoscopy were performed for some other reason, as it would not be routine to examine the ovaries in this way to confirm a diagnosis of PCOS).
- Serum (blood) levels of androgens (male hormones), including androstenedione, testosterone and Dehydroepiandrosterone sulphate may be elevated. The free testosterone level is thought to be the best measure, with ~60% of PCOS patients demonstrating supranormal levels.
- The Free Androgen Index (FAI) of the ratio of testosterone to sex hormone-binding globulin (SHBG), is meant to be a predictor of free testosterone, but is a poor parameter for this and is no better than testosterone alone as a marker for PCOS, possibly because FAI is correlated with the degree of obesity. There are often low levels of SHBG, particularly among obese women.
Common assessments for associated conditions or risks
- Fasting biochemical screen and lipid profile
- 2-hour oral glucose tolerance test (GTT) in patients with risk factors (obesity, family history, history of gestational diabetes) and may indicate impaired glucose tolerance (insulin resistance) in 15-30% of women with PCOS. Frank diabetes can be seen in 65–68% of women with this condition. Insulin resistance can be observed in both normal weight and overweight patients.
- Fasting insulin level or GTT with insulin levels (also called IGTT). A hypoglycemic response in which the two-hour insulin level is higher and the blood sugar lower than fasting is consistent with insulin resistance. Elevated insulin levels have been helpful to predict response to medication and may indicate women who will need higher dosages of metformin to lower insulin levels. Elevated blood sugar and insulin values do not predict who responds to an insulin-lowering medication, low-glycemic diet, and exercise.
Glucose tolerance testing (GTT) instead of fasting glucose can increase diagnosis of increased glucose tolerance and frank diabetes among patients with PCOS according to a prospective controlled trial. While fasting glucose levels may remain within normal limits, oral glucose tests revealed that up to 38% of asymptomatic women with PCOS (versus 8.5% in the general population) actually had impaired glucose tolerance, 7.5% of those with frank diabetes according to ADA guidelines.
For exclusion of other disorders that may cause similar symptoms:
- Prolactin to rule out hyperprolactinemia
- TSH to rule out hypothyroidism
- 17-hydroxyprogesterone to rule out 21-hydroxylase deficiency (congenital adrenal hyperplasia). Many such women may appear similar to PCOS and be made worse by insulin resistance or obesity, but they can be greatly helped by adrenal suppression with low-dose glucocorticoid therapy.
Other causes of irregular or absent menstruation and hirsutism, such as congenital adrenal hyperplasia, Cushing's syndrome, hyperprolactinemia, androgen secreting neoplasms, and other pituitary or adrenal disorders, should be investigated. PCOS has been reported in other insulin resistant situations such as acromegaly.
Polycystic ovaries develop when the ovaries are stimulated to produce excessive amounts of male hormones (androgens), particularly testosterone, either through the release of excessive luteinising hormone (LH) by the anterior pituitary gland or through high levels of insulin in the blood (hyperinsulinaemia) in women whose ovaries are sensitive to this stimulus.
The syndrome acquired its most widely used name due to the common sign on ultrasound examination of multiple (poly) ovarian cysts. These "cysts" are actually immature follicles, not cysts ("polyfollicular ovary syndrome" would have been a more accurate name).
Insulin resistance and PCOS
PCOS is characterised by a complex set of symptoms, and the cause cannot be determined for all patients. However, research to date suggests that insulin resistance could be a leading cause. PCOS may also have a genetic predisposition, and further research into this possibility is taking place. No specific gene has been identified, and it is thought that many genes could contribute to the development of PCOS.
Also, hyperinsulinemia increases GnRH pulse frequency, LH over FSH dominance, increased ovarian androgen production, decreased follicular maturation, and decreased SHBG binding; all these steps lead to the development of PCOS. Insulin resistance is a common finding among patients of normal weight as well as those overweight patients.
Obesity and PCOS
A majority of patients with PCOS have insulin resistance and/or are obese. Their elevated insulin levels contribute to or cause the abnormalities seen in the hypothalamic-pituitary-ovarian axis that lead to PCOS. Adipose tissue possesses aromatase, an enzyme that converts androstenedione to oestrone and testosterone to oestradiol. The excess of adipose tissue in obese patients creates the paradox of having both excess androgens (which are responsible for hirsutism and virilization) and oestrogens (which inhibits FSH via negative feedback). Inflammation PCOS may be associated with chronic inflammation, with several investigators correlating inflammatory mediators with anovulation and other PCOS symptoms.
- Medical treatment of PCOS is tailored to the patient's goals.
- Lowering of insulin levels
- Restoration of fertility
- Treatment of hirsutism or acne
- Restoration of regular menstruation, and prevention of endometrial hyperplasia and endometrial cancer.
General interventions that help to reduce weight or insulin resistance can be beneficial for all these aims, because they address what is believed to be the underlying cause of the syndrome.
Insulin lowering diet
Where PCOS is associated with overweight or obesity, successful weight loss is the most effective method of restoring normal ovulation/menstruation, I recommend a vegan/vegetarian based (but not exclusive) Keto Diet.
Medications such as metformin, and the newer thiazolidinedione (glitazones) that reduce insulin resistance by improving insulin sensitivity through have been an obvious approach and initial studies seemed to show effectiveness.
Not all women with PCOS have difficulty becoming pregnant. For those who do, anovulation is a common cause. Ovulation may be predicted by the use of urine tests that detect the preovulatory LH surge, called ovulation predictor kits (OPKs). However, OPKs are not always accurate when testing on women with PCOS. Charting of cervical mucus may also be used to predict ovulation, or certain fertility monitors (those that track urinary hormones or changes in saliva) may be used. Methods that predict ovulation may be used to time intercourse or insemination appropriately. While not useful for predicting ovulation, basal body temperatures may be used to confirm ovulation.
For overweight women with PCOS, who are anovulatory, diet adjustments and weight loss are associated with resumption of spontaneous ovulation. For those who after weightloss still are anovulatory or for anovulatory lean women, clomiphene citrate and FSH are the principal treatments used to help infertility. The most drastic increase in ovulation rate occurs with a combination of diet modification, weight loss, and treatment with metformin and clomiphene citrate.
For patients who do not respond to clomiphene, diet and lifestylemodification, there are options available including assisted reproductive technology procedures such as controlled ovarian hyperstimulation with FSH injections and in vitro fertilisation (IVF).
Hirsutism and acne
When appropriate (e.g. in women of child-bearing age who require contraception), a standard contraceptive pill may be effective in reducing hirsutism. Other drugs with anti-androgen effects include flutamide and spironolactone, some improvement in hirsutism. Spironolactone is probably the most-commonly used drug in the US. Metformin can reduce hirsutism, perhaps by reducing insulin resistance, and is often used if there are other features such as insulin resistance, diabetes or obesity that should also benefit from metformin.
For removal of facial hairs, electrolysis or laser treatments are faster and more efficient alternatives than the above mentioned medical therapies.
Menstrual irregularity and endometrial hyperplasia
If fertility is not the primary aim, then menstruation can usually be regulated with a contraceptive pill. The purpose of regulating menstruation is essentially for the woman's convenience, and perhaps her sense of well-being; there is no medical requirement for regular periods, so long as they occur sufficiently often (see below). (a contraceptive pill containing cyproterone acetate) is also beneficial for hirsutism, and is therefore often prescribed in PCOS.
If a regular menstrual cycle is not desired, then therapy for an irregular cycle is not necessarily required - most experts consider that if a menstrual bleed occurs at least every three months, then the endometrium (womb lining) is being shed sufficiently often to prevent an increased risk of endometrial abnormalities or cancer.
Women with PCOS are at risk for the following:
- Endometrial hyperplasia and endometrial cancer (cancer of the uterine lining) are possible, due to overaccumulation of uterine lining, and also lack of progesterone resulting in prolonged stimulation of uterine cells by oestrogen. It is however clear if this risk is directly due to the syndrome or from the associated obesity, hyperinsulinemia, and hyperandrogenism
- Insulin resistance/Type II diabetes. A review published in 2010 concluded that women with PCOS had an elevated prevalence of insulin resistance and type II diabetes, also when controlling for body mass index(BMI).
- High blood pressure
- Dyslipidemia- disorders of lipid metabolism — cholesterol and triglycerides. PCOS patients show decreased removal of atherosclerosis-inducing remnants, seemingly independent on insulin resistance/Type II diabetes.
- Cardiovascular disease
- Weight gain
- Acanthosis nigricans (patches of darkened skin under the arms, in the groin area, on the back of the neck)
- Autoimmune thyroiditis
Natural Medicine causes of PCOS
- Insulin resistance
- Excess inflammatory mediators
- Decreased SHBG
- Serum insulin, insulin resistance and homocysteine levels are significantly higher in subjects having PCOS but have no significant effect on fertility.
- Poor enterohepatic function
- Pelvic congestion
Insulin resistance (IR) and PCOS
Insulin resistance (IR) is a physiological condition where the natural hormone, insulin, becomes less effective at lowering blood sugars leading to hyperglycaemia and resultant health problems. Certain cell types such as fat and muscle cells require insulin to absorb glucose. When these cells fail to respond adequately to circulating insulin, blood glucose levels rise. The liver helps regulate glucose levels by reducing its secretion of glucose in the presence of insulin. This normal reduction in the liver’s glucose production may not occur in people with insulin resistance.
IR is an essential pathophysiologic mechanism in the development of all metabolic complications of PCOS. Disturbances in the hypothalamus-hypophysis-ovary axis (HHOA) are a feature of PCOS, with increased frequency and amplitude of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH). Higher levels of this hormone induce greater androgen (male hormones) synthesis in ovarian theca cells. In turn, hyperandrogenemia (high androgens) induces a decrease in feedback sensitivity to both oestradiol and progesterone in gonadotropic hypothalamic cells, reinforcing GnRH and LH hypersecretion. This is a self-perpetuating pathophysiologic cycles
Hyperhomocysteinaemia and PCOS
Hyperhomocysteinaemia is a medical condition characterised by an abnormally large level of homocysteine in the blood. Hyperhomocysteinaemia is a risk factor for Coronary artery disease. Coronary artery disease is when plaque builds up inside the coronary arteries. These arteries supply the heart with blood. A high level of homocysteine makes a person more prone to have blood clots which may result in heart attacks and strokes. Hyperhomocysteinaemia also damages the linings of veins and arteries.
Studies have found that homocysteine levels are significantly higher in PCOS patients than in the controls. There is a strong association between serum homocysteine and insulin resistance in women with PCOS that contributes to the long-term complications of PCOS, since hyperhomocysteinemia is associated with early atherosclerosis.
Hypothalamic pituitary ovarian axis dysfunction
The hypothalamic-pituitary-gonadal axis ( HPG axis) is referring to the effects of the hypothalamus, pituitary gland and gonads as if these individual endocrine glands were a single entity as a whole.
The hypothalamic-pituitary-gonadal axis is a critical part in the development and regulation of a number of the body's systems, such as the reproductive, and immune systems. Fluctuations in the hormones cause changes in the hormones produced by each gland and have various widespread and local effects on the body. This axis controls development, reproduction, and aging in animals.
In relation to reproductive disorders such as PCOS, the hypothalamus produces gonadotropin-releasing hormone (GnRH). The anterior portion of the pituitary gland produces luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and the gonads produce oestrogen and testosterone.
Natural Medicine treatment principles for PCOS
- 1. Improve insulin sensitivity
- 2. Lower homocysteine levels
- 3. Regulate the hypothalamic-pituitary-ovarian-axis
- 4. Promote weight loss
- 5. Encourage regular exercise
- 6. Reduce inflammation
- 7. Increase Sex hormone Binding Globulin (SHBG)
Improve insulin sensitivity
Some of the best ideas for preventing and reversing insulin resistance come from emerging treatments for adult-onset diabetes, the condition in which insulin resistance is most severe. One approach aims at reducing glucose levels (and consequently insulin levels) and the other uses vitamins to counteract free radicals generated by glucose. Nutrients are involved as cofactors in insulin production and utilisation.
Herbal medicine to improve insulin sensitivity
Gymnema Gymnema sylvestre
Gymnema sylvestre is regarded as one of the plants with potent anti diabetic properties. The leaves of Gymnema have been used for treatment of diabetes, hypercholesterolemia, joint pain, and snake bites in India and China. The major bioactive constituents are gymnemic acids, a group of oleanane-type triterpenoid saponins including gymnemic acids I-VII, gymnema saponins and their derivatives. Gymnema lowers blood sugar ths imporves insulin sensitivity
Fenugreek Trigonella foenum-graecum
Fenugreek seed was a traditional remedy used by ancient Egyptians and spread to Asian countries such as China and India. Fenugreek seeds are a rich source of the polysaccharide galactomannan and also contain saponins such as diosgenin, yamogenin, gitogenin, tigogenin, and neotigogens. The hypoglycemic effects of Fenugreek are well know. Fenugreek lowers insulin levels thereby improving insulin sensitivity.
Zhijun Wang et al., Treating Type 2 Diabetes Mellitus with Traditional Chinese and Indian Medicinal Herbs., Evid Based Complement Alternat Med. 2013; 2013: 343594.
Stinging Nettle Urtica dioica
Stinging Nettle Urtica dioica has been used as antihypertensive, antihyperlipidemic and antidiabetic herbal medicine. Stinging nettle extract decreases serum glucose, thus lowering inulin levels and therby imporving insulin sensitivity.
Akram Ahangarpour et al., Antidiabetic Effect of Hydroalcholic Urtica dioica Leaf Extract in Male Rats with Fructose-Induced Insulin Resistance., Iran J Med Sci. 2012 Sep; 37(3): 181–186.
Try Carahealth Lipotropic Tonic
Chaste Tree Vitex agnus cactus, Milk thistle Silybum marinarum, Saw palmetto Serenoa serrulata , Nettle root Urtica dioica, Fenugreek Trigonella foenum-graecum
This tincture is formulated to address the causes of Polycystic Ovarian Syndrome (PCOS), which are excessive amounts of male hormones (androgens), produced by the ovaries and adrenal glands resulting from the release of excessive luteinizing hormone (LH) by the anterior pituitary gland or through high levels of insulin in the blood (hyperinsulinaemia). The mix also alleviates the symptoms, oligomenorrhea, amenorrhoea, chronic anovulation (lack of ovulation), hirsutism, male pattern baldness in women and acne, obesity, depression and a deepening of voice. The mix regulates the hormones and imporves insulin sensitivity.
Nutritional Supplements to Improve Insulin Sensitivity
Alpha-lipoic plays a fundamental role in converting glucose to energy. Researchers have known from animal experiments that it can lower and stabilise glucose levels and, in Germany, alpha-lipoic acid is sold as a "drug" for the treatment of diabetic polyneuropathy, a type of severe nerve pain. Alpha-lipoic acid stimulates insulin activity, which safely lowers and stabilises glucose levels. It also improves insulin sensitivity and increases glucose tolerance.
Vanadium, found in vanadyl sulfate supplements, also improves insulin's ability to transport glucose into cells. With insulin working efficiently, the body needs and produces less of it.
Chromium helps lower glucose levels as it is a component of the "glucose tolerance factor," a molecule essential for normal insulin function and glucose metabolism. 200 mcg of chromium picolinate daily safely lowers and stabilises blood sugar levels in diabetics in just four months. Taking 1,000 mcg of chromium daily leads to glucose and insulin levels comparable to those of normal people.
Zinc is involved in virtually all aspects of insulin metabolism including synthesis, secretion and utilisation. Zinc also has a protective effect against beta cell destruction in the pancreas, and has well-known anti-viral effects. People with insulin resistance and Type 2 diabetes (NIDDM) also have low zinc levels, caused by excess loss of zinc in their urine, which may impair immune function. Specifically in realtion to PCOS, zinc is a natural 5 alpha reductase inhibitor and inhibits the conversion of testosterone to a stronger masculinising testosterone called dihydrotestosterone.DHT. Zinc (15-50 mg per day) is recommended. Take zinc with food to prevent stomach upset. If you take over 30 milligrams of zinc on a daily basis for more than one or two months, you should also take 1 to 2 milligrams of copper each day to maintain a proper mineral balance.
Omega-3 fatty acids
The omega-3 fatty acids, or fish oils, also improve insulin sensitivity and reduce insulin resistance, according to a recent animal study by Margaret T. Behme, M.D., of University Hospital, London, Ontario. The omega-3 fatty acids restore a balance disrupted by excessive consumption of omega-6 fatty acids and saturated fats. Vitamin E Vitamin E as a powerful antioxidant prevents "oxidative stress" caused by excessive glucose and free radicals in diabetics and insulin resistant patients.
D-chiro-inositol (DCI) offers a well-tolerated and effective alternative treatment for PCOS. It has been evaluated in two peer-reviewed, double-blind studies and found to help both lean and obese women with PCOS; diminishing many of the primary clinical presentations of PCOS. It has no documented side-effects and is a naturally occurring human metabolite known to be involved in insulin metabolism.
Research has shown the Maitake mushroom (Grifola frondosa) has a hypoglycemic effect, and may be beneficial for the management of diabetes and insulin resistance. The reason Maitake lowers blood sugar is due to the fact the mushroom naturally acts as an alpha glucosidase inhibitor. Other mushrooms like Reishi, Agaricus blazei, Agrocybe cylindracea and Cordyceps have been noted to lower blood sugar levels to a certain extent, although the mechanism is currently unknown.
As a consequence of the biochemical reactions in which homocysteine is involved, deficiencies of the vitamins folic acid, pyridoxine (B6), or B12 can lead to high homocysteine levels. Supplementation with pyridoxine, folic acid, B12 or trimethylglycine (betaine) reduces the concentration of homocysteine in the bloodstream.
Regulate the Hypothalamic Pituitary Ovarian axis
HPO Regulators (Hypothalamus-Pituitary-Ovarian) include the herbs Black Cohosh Cimicifuga racemosa, and Chaste berry Vitex Agnus castus. Black Cohosh treats arthritis aches and pains, menopause hot flashes, painful periods, thinning of the vaginal wall and PMS. Vitex is a prime herb for the treatment of PMS and hormonal irregularity.
Where PCOS is associated with overweight or obesity, successful weight loss is the most effective method of restoring normal ovulation/menstruation, Some experts recommend a low GI diet in which a significant part of total carbohydrates are obtained from fruit, vegetables and whole grain sources. Regular exercise and maintaining a healthy weight will help reduce the hormonal imbalance, restore ovulation and fertility, and improve acne and hirsutism.
Dietary Advice for insulin resistance in PCOS
Eat foods high in fibre
Foods high in fibre help lower blood cholesterol. Oat bran, oatmeal, whole-grain breads and cereals, dried beans and peas (such as kidney beans, pinto beans, and black-eyed peas), fruits, and vegetables are all good sources of fibre.
Reduce saturated fat
Saturated fat raises blood cholesterol level. Saturated fat is found in meats, poultry skin, butter, dairy products with fat, shortening, lard, and tropical oils such as palm oil.
Coconut oil is the new olive oil
Coconut oil, as a virgin coconut oil, is cholesterol free. Coconut oil contains medium-chain triglycerides, when these are digested they go straight to the liver and are transformed into energy, not fat. Coconut oil contains fewer calories than many other oils and fats. Coconut oil is high in lauric acid, which is a key constituent of breast milk. Lauric acid is believed to have both anti–viral and anti–fungal properties, helping to prevent and treat health problems such as yeast infections and candida. Coconut oil oil has been used for centuries in Eastern Ayurvedic Medicine to prevent and treat conditions including diabetes, viral infections and cardiovascular problems. Coconut oil is thermogenic, which means it helps to increase the body’s metabolism, contributing to increased energy levels and weight loss.
Avoid trans/ hydrogenated fats
Trans fats raises blood cholesterol. They are often in crackers, biscuits, snack foods, commercially prepared baked goods, cake mixes, microwave popcorn, fried foods and even salad dressings. Some margarines have trans fat. Check the label for trans fat. Some big chains are now cottoning on that we want these removed.
Increase physical activity
Aim for at least 30 minutes of exercise most days of the week. Think of ways to increase physical activity, such as taking the stairs instead of the elevator. Reach and maintain a healthy body weight Being a healthy weight range can lower your risk of diabetes, heart disease and stroke but even many types of cancer including colon, breast and prostate.
Inflammatory cytokines such as tumour necrosis factor alpha play a role in the pathophysiology of PCOS. Basically, limit pro-inflammatory foods and eat liberal amounts of anti-inflammatory foods.
Anti-inflammatory Food List
Fresh fish: mackerel, sardines, tuna, salmon, trout, and oily fatty fish types.
Colourful fresh vegetables: tomatoes, peppers, peas, spinach, kale, parsley, radishes, carrots (raw), celery, onions, garlic, cucumbers, etc
Colourful fresh fruit: apples, pears, kiwi, oranges (not juiced), grapefruit, peaches, plums, melons, strawberries, blueberries, blackberries, currants, many others
Lean chicken, turkey, well trimmed grass-fed beef and bison, venison
Dried nuts, seeds, beans
Herbs and spices (no salt)
Green and brown teas, extra virgin olive oils
Fish Oil, Omega-3EPA/DHA Borage Oil, GLA
Green tea, EGCG
Limit Pro-inflammatory Foods
Pro-inflammatory Foods List
Fatty meat, chops, hamburger, butter, margarine, most cooking and omega-6 vegetable oils, including soybean, corn, safflower, sunflower, peanut, cottonseed oils and many others
All grain fed meats, farm raised fish. All fried foods, grilled or BBQ meats
All dairy products, milk and eggs
High Fructose Corn Syrup, HFCS, simple carbohydrates: sugars, pasta, rice, potatoes, breads, pastries
Alcohol, tobacco and other addictive habits.
Avoid harsh cleaning fluids containing SLEs and parabens
Compounds in herbs and food act as natural anti-inflammatories including quercetin, berberine, genestin etc which act to inhibit COX and LOX and lower inflammatory mediators such IL6 and TNF alpha. For more detailed information on how inflammation leads to excess and overgrowth,
Carina's Keto Diet for Health & Longevity
This diet is a carbohydrate restrictive, high good fat, high healthy protein (including veg/vegan based protein) diet. Ketosis is a perfectly normal metabolic process. When we are unable to use carbohydrates as fuel for cells to burn for energy, fats are used instead. Ketones are produced as part of this process. In fact, ketones are the preferred source of fuel for our bodies. This diet is suitable for vegetarians/vegans.
Benefits of a Keto Diet
Lowers cholesterol: Both LDL & triglyceride levels
Induce Rapid Weight Loss: Promotes fat burning
Lowers Blood Sugar: Studies show a ketosis diet can eliminate type 2 diabetes
Improves insulin sensity and decreases insulin resistance: hyperinsulinemia increases GnRH pulse frequency, LH over FSH dominance, increased ovarian androgen production, decreased follicular maturation, and decreased SHBG binding; all these steps lead to the development of PCOS
Improves Energy: Fats are our most efficient fuel
Suppresses Hunger: High fats diets increase satiety
Starve Cancer Cells: Cancer cells need glucose for fuel. Only healthy cells can live on ketones. Studies indicate a ketosis diet is a therapeutic aid in cancer.
Treats neurodegenerative disease: Ketosis is being prescribed as a neuroprotective agent & therapeutic treatment in traumatic head injury, neurological disease including Alzheimer's & epilepsy, ALS, MS etc
Extends Life: The benefits of Calorie restriction/Keto diet are scientific fact. A Ketosis diet simulates the Calorie Restrictive Diet that scientists have touted for the main reason behind Okinawan longevity. Like CR, Ketosis also activates telomerase the anti-ageing enzyme. Calorie restriction increases telomerase activity and enhances autophagy (breakdown of dead cells). CR improves how cells respond to stress, how they break down (autophagy), induces apoptosis (programmed cell death ie in cancer cells), and alters hormonal balance. Autophagy in particular, is quality control inside cells. It is essential for the maintenance of cellular homeostasis and for the orchestration of an efficient cellular response to stress. Autophagic activity declines with age, and this contributes to the ageing process.
Rapid Weight Loss/Keto Diet for Health & Longevity also aims to;
Stabilises blood sugar to reduce cravings for carbohydrates.
Improves insulin sensitivity to treat Metabolic Syndrome & address central obesity.
Promotes bile flow from the liver to assist fat metabolism & address a “Sluggish Liver”.
Tonifies the thyroid gland to boost the Basal Metabolic Rate (BMR).
Addresses the mental emotional disorders that lead to comfort eating & food addiction.
Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to sex hormones, specifically testosterone and oestradiol. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin. Conditions with low SHBG include polycystic ovary syndrome diabetes, and hypothyroidism. Conditions with high SHBG include pregnancy, hyperthyroidism and anorexia nervosa. There has recently been research to link high SHBG levels with breast and testicular cancer as well.
A low fat high fibre diet with regular exercise naturally increase SHBG and decreases the risk of hormone dependant cancers TymchukCN,etal., Effects of diet and exercise on insulin, sex hormone-binding globulin,andprostate-specificantigen. Nutr Cancer 1998;31(2):127-31.
Increase isoflavones found naturally in soy products such as tofu and tempeh, chickpeas and kudzu root. Isoflavones are phytoestrogenic therfore protect the body from the negative effects pf oestrogen excess. They also increase SHBG. Brassicacaea family vegetables such as brocolli, cauliflower,cabbage, curly kale, pakchoi ect., also increase SHBG thereby improving the removal of excess hormones form circulation.Nettle root also normalises SHBG. See below.
A pilot study has also found evidence that Tai Chi and Qigong reduce the severity of type 2 Diabetes
Carina Harkin BHSc.Nat.BHSc.Hom.BHSc.Acu.
Cert IV TAE. ARCHTI mem.